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Aviptadil Acetate

CAS No. 1444827-29-5

Aviptadil Acetate( Vasoactive Intestinal Peptide acetate salt )

Catalog No. M23606 CAS No. 1444827-29-5

Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Aviptadil Acetate
  • Note
    Research use only, not for human use.
  • Brief Description
    Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation.
  • Description
    Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmonary fibrosis, pulmonary hypertension (PAH), and respiratory failure caused by SARS-CoV-2.
  • In Vitro
    Aviptadil acetate (1 nM-10 μM) produces a concentration-dependent inhibition of CSE-induced cell death in L2 cells. At 10 μM,Aviptadil acetate reduces CSE-stimulated MMP activity and caspase-3 activation in L2 cells.
  • In Vivo
    ——
  • Synonyms
    Vasoactive Intestinal Peptide acetate salt
  • Pathway
    Endocrinology/Hormones
  • Target
    RAAS
  • Recptor
    ACE|SARS-CoV-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1444827-29-5
  • Formula Weight
    3344.9
  • Molecular Formula
    C147H239N43O42S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:95mg/mL (28.06 mM)
  • SMILES
    HSDAVFTDNY TRLRKQMAVK KYLNSILN(acetate salt)
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Frye BC, Meiss F, von Bubnoff D, Zissel G, Müller-Quernheim J. Vasoactive Intestinal Peptide in Checkpoint Inhibitor-Induced Pneumonitis. N Engl J Med. 2020;382(26):2573-2574. doi:10.1056/NEJMc2000343
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